Search results for " Williams"
showing 10 items of 21 documents
Achados orais na síndrome de williams-beuren
2017
Background: Williams-Beuren syndrome (WBS; OMIM #194050) is a developmental disorder characterized by congenital heart disease, intellectual disability, dysmorphic facial features and ophthalmologic abnormalities. Oral abnormalities are also described in clinical manifestations of the disease. This paper describes orofacial features in patients with WBS. Material and Methods: Seventeen patients with a confirmed molecular diagnosis of WBS were examined for oral abnormalities through clinical oral evaluations and panoramic radiography. Results: Malocclusion, specifically with dental midline deviation, and high-arched palate were the most common findings. Conclusions: The present results contr…
Adaptive BEM for Low Noise Propeller Design
2009
A potential-based Boundary Element Method is presented for the aerodynamic and acoustic design of propel- lers at on- and off-design point conditions. Using an adaptive method, a family of airfoil sections is selected to produce the required performance (thrust, torque and efficiency versus advance ratio) at different cruise flight levels. Climb condi- tions are also considered in order to check the off-design point performance. Once the available airfoil data have been stored in a database, the code processes the families of airfoils to generate a complete geometry for a propeller of the specified performance with an optimized noise emission. The computational scheme adjusts the blade geom…
Evolution of the Human chromosome 7: new information from the mapping of William-Breuren locus on non human primates chromosomes.
2004
Human chromosome 7 (HSA7) derives, by a pericentric inversion and a paracentric inversion, from an ancestral chromosome homologous to chromosome 10 of Pongo pygmaeus (the Asiatic Orang-Utan). Nevertheless the genesis of this autosome during primates evolution is not clear. Even if chromosome painting shows that HAS 7 synteny is highly conserved, GTG-banding comparison in Hominoidea and Cercopithecoidea indicates the probable occurrence of complex rearrangements during the evolution. In this study we used a single locus FISH approach, a powerful tool to detect fine rearrangements, in order to investigate the evolution of HAS 7. We report the chromosome mapping of Williams-Beuren syndrome loc…
Self-knowledge, Authenticity and Obedience
2014
In questo articolo propongo un descrizione del privilegio epistemico dato alla prospettiva della prima persona, alla quale si relaziona un certo tipo di potere su sé stessi. Vorrei mettere in discussione il punto di vista di Robert Dumm e Richard Moran sul problema del soggetto e abbozzare un approccio alternativo. A tal fine, vorrei per prima cosa avvalermi delle nozioni di Bernard William di riconoscimento e di donazione di senso e, in secondo luogo, utilizzare la distinzione di Simone Weil tra i due sensi di obbedienza e la nozione, ad essa associata, di attenzione. In contrasto con la visione di Moran e Dunn, concluderei affermando che un certo tipo di autopercezione è centrale nel nost…
Reshaping Monetary Policy after the Great Crash: John H. Williams at the NY FED
2020
John H. Williams was an influential economist and central banker in the interwar years. A Harvard University professor since 1929 specialized in international trade and monetary economics, he joined the NY Fed in 1933 and became its vice-President in 1936. This paper aims to provide a general assessment of Williams’ contributions to monetary and fiscal policy during his tenure at the NY FED. We shall try to do so by following a twofold perspective: i. establish connections between Williams’ more theoretical works, his interpretations of the great depression and some policy decisions enacted by the FED in the 1930s; ii. provide new archival evidence on what was the part Williams played in th…
Chromosomal Dynamics in Cercopithecini Studied by Williams-Beuren probe mapping
2010
Chromosomal evolution in the tribe Cercopithecini and in related taxa is highly debated. Uncertainty in reconstruction is mainly related to the great genetic variability and polymorphism of the taxa. Recent molecular and karyological efforts individuate a split between genetically conservative, arbitrarily defi ned, “terrestrial” guenons and vervets, and genetically variable and derived “arboreal” guenons. We performed the mapping of WS loci probe (7q11.23) in order to verify the chromosomal dynamics of the genomes of three tree-dwelling species of the tribe: C. neglectus, C. mitis mitis, C. albogularis labiatus. Data from literature for the “ground-dwelling” Chlorocebus aethiops sabaeus ha…
Exploring Evolution in Ceboidea (Platyrrhini, Primates) by Williams-Beuren Probe (HSA 7q11.23) Chromosome Mapping
2007
The ancestral platyrrhine karyotype was characterised by a syntenic association of human 5 and a small segment of human 7 orthologues. This large syntenic association has undergone numerous rearrangements in various phylogenetic lines. We used a locus-specific molecular cytogenetic approach to study the chromosomal evolution of the human 7q11.23 orthologous sequences (William-Beuren syndrome, WS) in various Ceboidea (Platyrrhini) species. The fluorescent in situ hybridisation of the WS probe revealed a two-way pattern of chromosomal organisation that suggests various evolutionary scenarios. The first pattern (seen in Callimico and Saimiri ) includes a fairly simple disruption of the 7/5 syn…
HARVARD MEETS THE CRISIS: THE MONETARY THEORY AND POLICY OF LAUCHLIN B. CURRIE, JACOB VINER, JOHN H. WILLIAMS, AND HARRY D. WHITE
2015
The paper discusses the interpretation of the Great Depression and the policy decision making by four Harvard economists: Lauchlin B. Currie, Jacob Viner, John H. Williams, and Harry D. White. All were eminent scholars in the field of monetary and international economics, and were deeply involved in policy decisions during the New Deal. We will discuss how their Harvard training provided them with a common methodological and analytical perspective, and how this common perspective translated into specific policies when they moved from the academia to public service in the US administration. Their interpretation of the causes of the Great Depression and their policy proposals show the eclecti…
Effect of intermittent exposure to ethanol and MDMA during adolescence on learning and memory in adult mice
2012
Abstract Background Heavy binge drinking is increasingly frequent among adolescents, and consumption of 3,4-methylenedioxymethamphetamine (MDMA) is often combined with ethanol (EtOH). The long-lasting effects of intermittent exposure to EtOH and MDMA during adolescence on learning and memory were evaluated in adult mice using the Hebb-Williams maze. Methods Adolescent OF1 mice were exposed to EtOH (1.25 g/kg) on two consecutive days at 48-h intervals over a 14-day period (from PD 29 to 42). MDMA (10 or 20 mg/kg) was injected twice daily at 4-h intervals over two consecutive days, and this schedule was repeated six days later (PD 33, 34, 41 and 42), resulting in a total of eight injections. …
The Subtle Residual: Baroque Echoes in The Scarlet Letter
2021
The following essay analyzes a significant Baroque substrata underlying The Scarlet Letter, taken up, among other things, in relation to the momentous Puritan legacy that is an essential element of Nathaniel Hawthorne’s literary work. In particular, the paper focuses on analyzing crucial and minor Baroque topoi represented in the novel, such as metamorphosis, relativism and ambivalence of reality, anxiety and the obsession with death. Furthermore, the article investigates the role of sharp chromatism within The Scarlet Letter, the use of typical Baroque symbols, such as the ellipse and the maze, and the fundamental role of distinctive Baroque tropes, that is, metaphor and antithesis. In ord…